Skin and Mucous Membranes: Pruritus, vaginitis, angioedema and rare instances of exfoliative dermatitis have been reported.Cases of Acute Generalized Exanthematous Pustulosis (AGEP), erythema multiforme, some resembling Stevens-Johnson syndrome, anaphylactic shock, anaphylactic reaction and hypersensitivity have also been reported. Severe skin reactions such as Toxic Epidermal Necrolysis, some with fatal outcome, have been reported. Vesiculobullous rashes, as well as urticaria, have been observed during drug therapy. Hypersensitivity Reactions: Generalized mild to moderate morbilliform-like (maculopapular) skin rashes are the most frequently reported adverse reactions.An unpleasant or metallic taste has been reported after oral administration. The onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment. Gastrointestinal: Abdominal pain, pseudomembranous colitis, esophagitis, nausea, vomiting, and diarrhea.Infections and Infestations: Clostridium difficile colitis.The following reactions have been reported with the use of clindamycin. Cleocin should not be used during the first trimester of pregnancy unless it is clearly needed because it has not been properly evaluated during the first trimester of pregnancy.Ĭleocin is excreted in breast milk and should not be used by nursing mothers or breastfeeding should be stopped.Ĭleocin (clindamycin) side effects list for healthcare professionals The frequency of congenital abnormalities was not increased when pregnant women used Cleocin during the second and third trimesters.
This means it can increase the action of neuromuscular blocking drugs. inflammation of the colon (pseudomembranous colitis symptoms include diarrhea, fever, abdominal pain, and possibly shock),ĭrug interactions of Cleocin include neuromuscular blocking drugs (for example, pancuronium and vecuronium, which are used during surgery) because Cleocin may act as a neuromuscular blocker.Clostridium difficile associated diarrhea (CDAD) which causes.It reduces growth of bacteria by interfering with their ability to make proteins. It is effective against several types of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus epidermidis, and Propionibacterium acnes. It is most often used to treat penicillin- allergic patients or in other situations where penicillin or other alternative antibiotics cannot be used.Įxamples of infections that are treated with Cleocin include serious respiratory tract infections (for example, empyema, pneumonitis, and lung abscess), serious skin and soft tissue infections, and female pelvic and genital tract infections (for example, endometritis), and ovarian abscess. Does Cleocin (clindamycin) cause side effects?Ĭleocin ( clindamycin) is an oral antibiotic used to treat serious infections caused by susceptible bacteria.
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